Laugierhunziker syndrome in a patient with rheumatoid. Laugierhunziker syndrome is a rare benign condition characterized by diffuse oral hyperpigmentation associated with pigmentation of the nails. Dylan hunziker 2014 center for international education. Laugierhunziker syndrome lhs, also termed idiopathic lenticular mucocutaneous hyperpigmentation is an unusual condition characterized by progressive pigmentation of the mucous membranes. His approach is to discuss some familiar aspects of renaissance and. Laugier hunziker syndrome lhs is an infrequent disorder, characterized by brown macular hyperpigmentation as a grayish brown lentiginous macules of about 5 mm, of the lips and oral. For additional information on treatment options for laugierhunziker syndrome or the candela vbeam pulsed dye laser, please contact florida skin center. Essai sur larchitecture essay on architecture defects of columns. If you have problems viewing pdf files, download the latest version of adobe reader for language access assistance, contact the ncats public information officer genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree.
Herein, we reported a 45yearold female case with lhs. Laugierhunziker syndrome lhs was initially described in 1970 as acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with longitudinal melanonychia. Three pediatric patients are reported and literature case report are discussed. Four cases of laugierhunziker syndrome are described. Ayoub n, barete s, bouaziz jd, le pelletier f, frances c. Cest relativement rare et aucun traitement nest a faire hormis une surveillance. Laugierhunziker syndrome lhs, a rare, acquired pigmentary disorder of the lips, oral mucosa, and fingers, is known to be an entirely benign disease with no systemic manifestations. In all patients two men and two women between 39 and 57 years of age pigmentation of the lower lip and hard palate was found. He was the son of an apothecary who began an apprenticeship in this field, but then became a medical student. Additional conjunc tival and penile pigmentation in laugierhunziker syndrome.
Discussion the laugierhunziker syndrome is a rare condition initially described in 1970 involving di. Geneanet is a website which allows everyone to start or to go furtther in their family tree. In laugierhunziker syndrome, no systemic manifestations have been described so far. Essai sur larchitecture work by laugier britannica.
In addition, periorificial pigmentation around the mouth, nose and eyes are classically seen, whereas the lesions of the laugierhunziker syndrome are con fined to intraoral surfaces. Interested in botany, he went to vienna, at the request of the last duke of lorraine, to direct the botanical garden. Laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules. Alkhadhari, md department of dermatology, farwaniya hospital, ministry of health, kuwait abstract we describe a 47yearold woman referred to laser department for the management of. It undertakes to study a real object in the natural world the brain, its states, and its functions and thus to move the study of the mind towards eventual integration with the biological sciences. Dylan hunziker 2014 hunziker, a sociology major, said, i have been waiting for an opportunity like the watson ever since i opened my first chinese book nine years ago. There is no evidence of genetic transmission or spontaneous resolution. Abstract laugierhunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugierhunziker syndrome is a cutaneous condition characterized by hyperpigmentation of. What links here related changes upload file special pages permanent link page. Charles laugier historical records and family trees. Laugierhunziker pigmentation lhp is an acquired disorder of hypermelanosis characterized by mucocutaneous hyperpigmentation. The average age of the reported cases at diagnosis is 47. In 1970, laugier and hunziker reported five cases of an unusual acquired macular hyperpigmentation with no underlying disease and two of these patients also displayed longitudinal pigmented streaks on the nails.
Theory excerpts marcantoine laugier, essai sur larchitecture 1753 wolfgang and anni herrmann, trans. Laugierhunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugierhunziker syndrome the pan african medical journal. Laugier and hunziker were the first to describe a syndrome characterized by acquired macular hyperpigmentation of the oral mucosa and lips. General principles of architecture it is the same in architecture as in all other arts. Two cases of laugierhunziker syndrome with thrombocytopenia. There are approximately 200 reported cases in the literature. It is important to differentiate this condition from the pigmentary disorders of the oral mucosa. Since then several similar cases have been reported showing involvement of all regions of the oral cavity, including lips, tongue, buccal mucosa, gingiva. Pan african medical journal images in clinical medicine.
Hyperpigmentation in laugierhunziker syndrome cmaj. Essai sur larchitecture by laugier, marcantoine, 17111769. Listen to the audio pronunciation of laugierhunziker syndrome on pronouncekiwi. Charles laugier, 1730 1731 charles laugier 1730 1731 charles laugier was born on month day 1730, at birth place, to pierre laugier and marguerite laugier. A case of laugierhunziker syndrome to appear in infancy or early childhood and occur most commonly on the lips and oral mucosa. Laugierhunziker syndrome lhs is a rare, benign, acquired pigmentary condition mainly affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. Summary laugier hunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. We present the case of a 63yearold female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7year history of hyperpigmentation in several fingernails. The laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal. Research laugier in the surnames forums on, the new genforum. The cognitive revolution renewed and reshaped many of the insights. Laugierhunziker syndrome was described in a patient with ovarian cancer during polychemotherapy, but this occurrence was considered to be incidental. Our laugierhunziker syndrome patient had significant improvement after one treatment. Laugierhunziker syndrome lhs is a rare acquired disorder characterized by diffuse macular hyperpigmentation of the oral mucosa and, at times, longitudinal melanonychia.
Publication date 1755 topics architecture, architecture early works to 1800 publisher. Observations sur larchitecture by laugier, marcantoine, 17111769. Laugierhunziker syndrome symptoms, causes, diagnosis, and treatment information for laugierhunziker syndrome laugierhunziker syndrome with alternative diagnoses, fulltext book chapters, misdiagnosis, research treatments, prevention, and prognosis. Arch orofac sci case report laugierhunziker syndrome. Lhs displays a benign course and is not associated with malignancy.
Here we present a case of lhs with a 7year followup. Laugierhunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. Laugier and hunziker described a syndrome consisting of asymptomatic benign areas of hyperpigmentation affecting the lips, buccal mucosa and, in 50 %, the fingernails. Advocating a return to rationalism and simplicity in building and taking the primitive hut as his example of the fundamental expression of human needs, laugier was. Extended mucocutaneous features have been observed since that original description, including macular pigmentation of the genitalia. Le savoir est pour pour tous, et tous les citoyens doivent en profiter. We document metachronous oral melanoacanthomas in this. Based on the classicistic theory, laugiers radical system of rules rejected all the elements of the confusing and bizarre laugier, 1753, an not only the ones belonging to rococo, but also the fig.
Laugierhunziker syndrome is an acquired disease, characterized by mucocutaneous hyperpigmentations, which was first described by hunziker and laugier in 1970. Additional conjunc tival and penile pigmentation in laugier hunziker syndrome. French jesuit, marcantoine laugier, whose essai sur larchitecture appeared in french in 1753 and in english in 1755. Laugier hunziker syndrome lhs is an idiopathic macular hyperpigmentation of skin characterized by brownish black spots on oral mucosa including lips associated with longitudinal melanonychia of nails. Lhp may resemble various disorders characterized by mucocutaneous pigmentation.
The absence of systemic features and involvement at. Saikia diploma student, mathematics group the abdus salam international centre for theoretical physics 11, strada costiera trieste, italy email. Laugier hunziker syndrome, clinical picture 5870 laugier hunziker syndrome, clinical picture 5871 laugier hunziker syndrome, clinical picture 5872 laugier hunziker syndrome, clinical picture 5873 laugier hunziker syndrome, clinical picture 5874 laugier hunziker syndrome, clinical picture 5875 laugier. Other articles where essai sur larchitecture is discussed.
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